A framework towards implementation of sequencing for antimicrobial-resistant and other health-care-associated pathogens

Antimicrobial resistance poses a global threat, particularly in healthcare settings where it causes a significant proportion of healthcare-associated infections (HAIs). The 3rd Geneva Infection Prevention and Control Think Tank recommended a framework for sequencing HAI pathogens with antimicrobial resistance mechanisms. The framework includes wet laboratory quality, sequence data quality, database selection, bioinformatic analyses, data sharing, and NGS data integration.